Diabetic nephropathy is the kidney disease that results from diabetes mellitus. It is the most important cause of kidney failure.1

The diagnosis of diabetic nephropathy can be made by evaluating certain blood chemistry parameters that indicate kidney damage. The finding of protein in urine is also an early indication that your kidney is affected.1

Treatment of Diabetic Nephropathy

Maintaining the blood sugar levels and lowering the blood pressure are two extremely essential steps in the treatment of diabetic nephropathy.

Medications are usually prescribed for early stage of kidney failure which includes:2

1Controlling high blood pressure

Medicines belonging to the class angiotensin-converting enzyme (ACE) inhibitors or and angiotensin II receptor blockers (ARBs) are used to control the high blood pressure.

2Controlling sugar levels

Many medications help in controlling blood sugar in people with diabetic nephropathy.

3Decreasing high cholesterol

Statins are cholesterol-lowering drugs, which are used to treat high cholesterol.

4Controlling protein in urine

Medications are used to decrease the level of protein albumin in the urine and improve kidney function.

The advanced stages of kidney failure may require treatment with:1,3.4

Dialysis (an artificial process of removing waste products and excess fluid from the body)

Kidney transplant (transfer of a healthy kidney from one individual into the body of another individual who has little or no kidney function).


Prevention of diabetic nephropathy involves the treatment of its known risk factors, especially4

  • High blood pressure
  • High blood sugar
  • Smoking
  • Dyslipidemia (unhealthy levels of fats in your body)

The risk factors for diabetic nephropathy are similar to cardiovascular disease, and therefore should be vigorously treated.5

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